Ovarian rejuvenation treatment gains more and more attraction through the regenerative medicine and human reproduction field. As Crete Fertility Centre is one of the first fertility clinics applied this technique, its experience is an advantage for any woman who is willing to preserve the quality of the ovarian function, even after menopause. Below, the most common questions for ovarian rejuvenation are answered through a brief frequently asked questions (FAQ) quide that will give you better understanding to each aspect regarding the treatment.

1. What is Ovarian Rejuvenation?

Ovarian Rejuvenation is a regenerative treatment which targets to advance ovarian function and stimulate the development of new follicles. It is predominantly carried out using PRP (Platelet-Rich Plasma), enriched PRP (EnPRP), stem cells from adipose tissue, exosomes form adipose tissue or advanced combination protocols. Egg quality, hormonal balance and overall ovarian activity are the main targets to be attained.

2. Who is a suitable candidate?

Ovarian rejuvenation could be applied to women who:

• Own a low ovarian reserve (low AMH, high FSH)
• Experience premature ovarian insufficiency (POI)
• Respond poorly to IVF stimulation
• Go through an early menopause
• Wish to improve hormonal function and ovarian activity

Each case is individually assessed.

3. Can ovarian rejuvenation restore menopause?

If menopause is recent and ovarian atrophy is not entire, a hormonal improvement or temporary cycle restoration may be possible to occur. Nonetheless, in cases of long-term menopause (many years without menstruation), the chances of restoring fertility with own eggs is significantly low. Our top priority is to always provide a sincere medical assessment based on age, ultrasound findings, and hormonal profile.

4. What types of treatments are available?

At Crete Fertility Centre, the following traetments are provided:

• Standard Ovarian PRP
• Enriched PRP (EnPRP) – higher concentration of growth factors Stem Cell Therapy (from adipose tissue)
• Combination therapies (EnPRP + Stem Cells)
• Advanced protocol: EnPRP + Stem Cells + Exosomes
• Optional supportive therapy: Ovarian Boost IV

5. How is the procedure performed?

The whole procedure is effortless and pain- free.

It is conducted under mild sedation using a special ultrasound approach. Besides that, hospitalization is not required. Patients are allowed to leave the clinic the same day. What is advisable is a short stay in Crete which is usually one morning.

6. What tests are required before treatment?

Recent tests (within 2–6 months):

• Hormonal profile (FSH, LH, Estradiol – E2, AMH)
• Gynecological ultrasound (ovarian size and AFC)
• HIV, HBV, HCV, VDRL
• Complete blood count, glucose, urea, creatinine
• ECG

7. What are the success rates?

Success rates depend significantly on the following focal factors:

Age

Ovarian condition

Span of years since menopause (if applicable)

In designated cases, in a high ratio of patients, an apparent improvement in hormonal levels is tracked down. Pregnancy outcomes may vary and they are significantly age- related. After assessing your test results, a customized medical guidance is delivered.

8. Is the clinic certified?

Yes. Crete Fertility Centre is certified under the following standards:

• ISO 9001:2008 certified (since 2010)
• DIN-EN 15224 certified (highest healthcare quality standard)

These certifications can ensure safety and high-quality medical services.

9. How can I book a consultation?

You could send your medical history and current or recent test results to info@fertilitycrete.gr

You can request an online consultation and schedule an in-person appointment in Crete.

Our team will be at your disposal throughout the whole process.

10. How soon can I try to conceive after the treatment?

In most cases, we monitor hormonal levels and ovarian response during the first 1–3 months after the procedure. A natural pregnancy was accomplished after 1 month and even after 9 months. In vase that ovarian quality os enhanced, natural conception or IVF treatment can be undertaken promptly after medical assessment. Each case is approached individually based on the response to the treatment.

11. Is the procedure painful?

The treatment is performed under light sedation. It is pain-free and effortless. Patients have not repprted any pain during the whole process. Mild discomfort or light cramping may come up afterwards, but it usually overcome within 24–48 hours.

12. Are there risks or side effects?

No COMPLICATIONS have never been reported IN MORE THAN 5800 cases.

Since PRP utilizes patient’s own blood, the risk of allergic reaction is effectively eliminated.

13. Can the treatment improve menopausal symptoms?

Yes, in selected cases ovarian rejuvenation may assist in improving the following:

• improvement of hormonal level of FSH and E2
• reduction of hot flashes and sweating
• better sleep quality
• reduction of morning fatigue
• better joint flexibility and reduced muscle pain
• enhanced skin tone
• improvemwnt of vaginal dryness
• enhanvement of swcual desire
• psychological boost

However, results may vary depending on age and ovarian reserve.

14. How many times can the treatment be performed?

In some cases, a pptential second PRP session can be deliberated after assessing patient’s response to the first session. This decision is made based on hormonal results and ultrasound findings.

15. What is the difference between PRP and Enriched PRP (EnPRP)?

Standard PRP contains concentrated platelets from your own blood. EnPRP is a more developed technique with a remarkably higher concentration of growth factors and cytokines. It is planned to augment and facilitate the regenerative process within the ovaries.

16. Can ovarian rejuvenation replace egg donation?

Egg donation could still provide women of advanced reproductive age or long-term menopause with remarkably higher pregnancy rates. Ovarian rejuvenation can be an alternative for women who aspire to attempt pregnancy with their own eggs, providing that medical requirements are fulfilled. Our top priority is ro assess all feasible options with transparency and medical responsibility.

17. Do you treat international patients?

We certainly do. The majority of our patients come from abroad. Crete Fertilite Centre is the destination for ovarian rejuvenation from USA, CANADA, DUBAI, SAUDI ARABIA, AUSTRALIA, FRANCE, ITALY, and GERMANY.

Our team assists in both online consultation and treatment arrangement. The required stay is mainly only a day.

18. What you can do for ovarian rejuvenation?

For women facing the symptoms of menopause, the exploration of ovarian rejuvenation and rest anti-aging treatments such as exosome therapy  reflects a high desire to support their reproductive health throughout all stages of life.

Crete Fertility Centre always provides cutting-edge fertility treatments and the ovarian rejuvenation approach offers sustainable preservation of the ovarian function both during and beyond the menopausal years.