Sperm Booster IV is a specialized preparation for improving semen parameters.

The quality and quantity of sperm are critical factors in male fertility. Low sperm concentration, reduced motility, abnormal morphology, and increased oxidative stress are common causes of reduced reproductive potential. The accumulation of free radicals can damage sperm DNA, while nutritional deficiencies further compromise sperm quality and viability.

The Sperm Booster IV, offered at the Crete Fertility Centre in collaboration with the Jovian Health Lab, is a specialized intravenous protocol administered before assisted reproduction programs. Its goal is to improve the sperm microenvironment by reducing oxidative stress, enhancing mitochondrial function, and supporting hormonal balance. In this way, the male body is prepared to achieve better sperm quality and functionality.

How Sperm Booster IV works

• Antioxidant protection
  Reduces oxidative damage affecting sperm DNA and motility. Enhanced antioxidant defense has been associated with improved semen parameters and higher fertilization rates.
• Mitochondrial support
  Mitochondria are the primary source of energy for sperm motility. Improved mitochondrial function is linked to higher motility and better sperm performance.
• Hormonal balance
  The supply of key micronutrients supports the physiological function of the hypothalamic–pituitary–testicular axis, contributing to a stable and healthy hormonal profile.
• Cellular regeneration
  Creates the conditions for improved spermatogenesis, as cells are supported with the necessary elements for renewal and maturation.

Comprehensive approach

The Sperm Booster IV offers men participating in fertility programs the confidence that they are approaching the process in the most complete way. When the body is in a state of nutritional sufficiency, reduced oxidative stress, and enhanced mitochondrial function, sperm quality improves, increasing the chances of success.

Choosing this preparation is not only a medical intervention; it represents a comprehensive strategy to support male reproductive health and optimize the response to fertility treatments.

Timing of administration of Sperm Booster IV

The Sperm Booster IV is recommended one day before fertilization attempts or semen collection. Some men choose to undergo 2–3 sessions during the preceding week for more comprehensive preparation. In addition, administration is also recommended afterwards, as supportive care to maintain sperm quality and support spermatogenesis.

Advanced Fertility Preparation Protocol – Comprehensive individualized preparation for men

The Advanced Fertility Preparation Protocol is designed for men who wish to optimize sperm quality and functionality before and after assisted reproduction programs. It is an individualized medical process tailored to each man’s metabolic and hormonal profile, combining nutritional guidance, targeted supplementation, and, when indicated, functional testing.

Individualized nutrition

Nutrition plans are tailored to each patient’s needs and do not follow generalized models. The objectives are:

• strengthening antioxidant defense to protect sperm DNA,
• reducing low-grade inflammation that may impair sperm quality and motility,
• improving immune balance,
• supporting gut health and the microbiome, which contribute to the absorption of key micronutrients (e.g., zinc, selenium, folate) and hormonal regulation.

Individualized supplementation

Supplementation protocols are defined individually, depending on deficiencies, biochemical parameters, and specific needs. The aims are:

• correcting nutritional insufficiencies affecting spermatogenesis,
• enhancing mitochondrial function for improved sperm motility,
• stabilizing hormonal balance, particularly within the hypothalamic–pituitary–testicular axis,
• creating a cellular environment that promotes the production of healthy, functional sperm.

Functional testing

For men seeking a more comprehensive assessment, the following indicative tests may optionally be performed:

• Oxidative Stress Profile: evaluation of oxidative burden affecting sperm quality.
• Hormonal & Methylation Profile: assessment of hormonal balance and DNA repair capacity.
• Gut Microbiome Mapping: analysis of the microbiome related to metabolic health, nutrient absorption, and inflammation.

These tests are optional and may also be performed in the patient’s country of residence. In addition, the medical team may recommend further specialized assessments depending on the individual profile.

Clinical significance of preparation

Individualized preparation before fertility treatments contributes to:

• Optimization of the testicular microenvironment, supporting spermatogenesis.
• Reduction of oxidative stress and inflammation, associated with DNA fragmentation and reduced sperm quality.
• Strengthening immune function, which impacts reproductive health and sperm parameters.
• Stabilization of hormonal balance, essential for normal spermatogenesis.
• Support after treatment, to maintain the benefits achieved and optimize reproductive capacity.

Oversight and coordination of Sperm Booster IV

Crete Fertility Centre works in close collaboration with Jovian Health Lab, ensuring scientifically validated and personalized preparation. Every stage – from intravenous therapy to nutrition, supplementation, and optional testing – is carefully designed and coordinated to maximize the effectiveness of fertility treatments and the overall success of the process.